Have a round white pill in a baggie or pillbox and you aren’t sure what it is? Trying to figure out what the loose white round pill with a numbered imprint in the bottom of your medicine drawer is? Pill with imprint 54 543 is White, Round and has been identified as Roxicet 325 mg / 5 mg. It is supplied by Roxane Laboratories, Inc. Roxicet is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesic combinations. Pill Identifier. Having trouble identifying your pills? Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare. Images of Imprint 54 543 pills including Roxicet and oxycodone / acetaminophen. Compare prices, print coupons, and view information for thousands of prescription drugs. Compare prices, print coupons, and view information for thousands of prescription drugs. Pill with imprint 54 543 is White, Round and has been identified as Acetaminophen and Oxycodone Hydrochloride 325 mg / 5 mg. It is supplied by Roxane Laboratories,Inc. Hi, I just acquired a few Roxicets. They are big white pills and have 54 543 imprinted on them. I'm no stranger to prescription pills, but these are my first Roxicets. I heard it might be more beneficial to insulfate it (as opposed to the fast acting benzos I usually take). Any advice on how to take it, and if so how much (whole pill/half. Description. Pill imprint 54 543 has been identified as oxycodone. oxycodone is manufactured by Roxane Laboratories,Inc. and belongs to the drug classification. Oxycodone, Acetaminophen Oral tablet drug summary. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Visit cvs.com for more details. Is 54 543 the same pill as oxycodone/apap 10325mg it is not apap it is perscribed to ppl sensitive to the apap the 54s are better then the 512s not quite sure why but the. 54 543 white round forums and articles.